A 3D virtual model of the PKMYT1–PROTAC–CRBN ternary complex depicting how Insilico Medicine’s bifunctional proteolysis-targeting chimera (PROTAC) D16-M1P2 (shown in yellow) inhibits membrane-associated tyrosine-threonine protein kinase 1 (PKMYT1, shown in…
NeurIPS 2025 hosted at the San Diego Convention Center San Diego – More than 24,000 machine learning experts gathered for the largest Neural Information Processing Systems (NeurIPS) conference to date,…
Primary immune thrombocytopenia (ITP) is an autoimmune condition where the body’s immune cells mistakenly attack platelets, the blood cells responsible for clotting, which can lead to life-threatening bleeding. Associated with…
Mirum Pharmaceuticals signed a definitive agreement to acquire Bluejay Therapeutics, a privately-held biotech company focused on viral and liver diseases. The transaction would add worldwide rights to brelovitug, a late-stage,…
A wireless, ontogenetic device that sends information directly to the brain has been developed by a team at Northwestern University. The soft, flexible device sits under the scalp, on top…
An international research team has uncovered a mechanism that protects nerve cells from a form of premature cell death known as ferroptosis. Headed by Prof. Marcus Conrad, PhD, director of…
Target deconvolution, particularly when paired with proteomics techniques, plays a crucial role in drug screening, covalent drug discovery, mechanism of action (MOA) discovery, and target identification. By using chemical proteomics,…
View eBook With the MiSeq™ i100 Series, Illumina continues to set the highest standards. Advancements in system design, sequencing chemistry, and data analysis deliver the simplest, fastest benchtop sequencing and…
San Diego – The results from Arc Institute’s inaugural Virtual Cell Challenge are in. The public competition, sponsored by Nvidia, 10x Genomics, and Ultima Genomics, declared not one, but two…
Trimethylamine (TMA), a molecule produced from dietary choline by gut bacteria, has been shown to block a key immune pathway and improve blood sugar control. This microbial molecule may provide…