In a recent article in Elsevier’s International Journal of Biological Macromolecules, scientists at Vignan’s Foundation for Science, Technology, and Research in India redefined the industrial potential of cyanobacteria through innovative…
Cleanrooms aren’t as clean as you may think. New research has found multiple taxonomic groups of microbial signatures that escaped detection by conventional, culture-dependent monitoring methods. While these signals reflect…
U.S. Pharmacopeia (USP), the independent organization that helps develop quality standards for pharmaceuticals, has launched new standards for viral vectors that they hope will help the rapidly developing field of…
Precipitation-based purification could help make therapeutic mAbs more accessible, according to the Gates Foundation, which has awarded $3.1 million to a team using the approach as part of an effort…
Alphafold interaction prediction between NUDT5 dimers (red) and PPAT tetramer (blue) While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of…
Startup companies should draw upon expertise early in process development to avoid losing time on repeating scale-up or manufacturing-quality batches. That’s according to Validogen, a contract developer specializing in the…
Accumulation on surfaces is a big problem for protein drug makers. Such interactions impact drug efficacy and stability and can result in the formation of aggregates that provoke dangerous allergic…
As demand for precision medicine accelerates, CAR T and CAR Treg cell therapies are emerging as crucial tools in the fight against cancer and autoimmune diseases. For Thomas Fellner, PhD,…
The downstream processing and purification of glycans has been challenging for biopharmaceutical manufacturers because of the intricate mixtures of sugars, nucleosides, and buffer molecules that are present after glycan synthesis.…
Highly pathogenic avian influenza A (H5N1, commonly known as HPAI or bird flu) is a formidable worldwide public health concern. With approximately a 100% mortality rate, the World Organization for…