Target deconvolution, particularly when paired with proteomics techniques, plays a crucial role in drug screening, covalent drug discovery, mechanism of action (MOA) discovery, and target identification. By using chemical proteomics,…
In a special edition of GEN Live to wrap up 2025, we are thrilled to welcome special guest Matthew Cobb, PhD, author of a wonderful new biography of Francis Crick,…
As mRNA-based therapeutics move beyond early vaccine successes to encompass diverse modalities, the expectations for manufacturers to deliver products with consistent purity and quality are rising. To that end, traditional…
Bringing a new therapy to market takes years and costs billions, leaving biopharma under increasing pressure to compress development timelines. Overcoming that inertia requires rethinking traditional approaches to identifying biomarkers,…
Accurate and timely genetic diagnosis remains a major challenge across clinical medicine, particularly for patients with rare, undiagnosed, or complex conditions. While short-read whole genome sequencing (WGS) has improved diagnostic…
Delivering advanced therapies to patients who need them requires an effective transition from lab-based cell therapy activity to manufacturing at scale. Robust, reproducible processes that can adapt to increasing demand…
Lentiviral vectors (LVVs) are widely used as a delivery system for ex vivo cell and gene therapies. In recent years, growing interest in using LVVs for in vivo therapies has…
Panelists: Jon Stokes, PhD Co-founder and CSO of Stoked BioAssistant Professor at McMaster University Panelist Jon Stokes, PhD Jon Stokes, PhD, is the co-founder and CSO of Stoked Bio and…
We are gearing up for our annual AI in Drug Discovery summit in a few days. So, for this episode, we focused on some recent AI news coverage. First, GEN…
Panelists: Nicholas Brown Senior Laboratory TechnicianCharles River Laboratories Panelist Nicholas Brown Brown joined Charles River in November 2022 after completing his bachelor’s degree from the University of Scranton. Brown started…